Battling severe depression in the wake of a suicide attempt, 46-year old Olivia hasn’t left her Chicago basement in two years. With one last chance at a new life, Olivia…

Dolly has gotten too comfortable at 600 pounds. There’s physical pain all over, and the skin apron pulling on her abdomen is miserable, but with her mom and others waiting…

For Julian and his wife, Irma, it was love at first sight. But in order to grow old together, Julian will have to overcome the food addiction that made him…

Through tough times, food has always been Tammy’s friend. But now she has gotten so big that her daughters and mother have moved home to care for her, and unless…

The four best reasons for Coliesa to live are her daughters. But after a heart attack and losing the love of her life in a car crash, Coliesa eats non-stop…

At 24 years old and over 600 lbs, Megan lives at home with her mom, who cooks for her since Megan can’t do much on her own; Megan must travel…

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley…

Seana is 23 and nearly 700 lbs, living at her mom’s house, depressed and anxious, her weight-gain threatening to take her last breath. Dr. Now can give her the tools…

Joyce needs home health care 24/7 and hasn’t left the house in years. But getting to Dr. Now in Houston is just the first step, and when he prescribes therapy…

Lindsey has a white picket fence, a loving husband and a great job, but her food addiction threatens to ruin everything; as she embarks on a weight loss journey to…

Liz has gone from being bedbound with lymphedemas on both legs, to standing and walking, but old fears are about to threaten her progress; if Jenn and Marissa can’t get…

For Milla Clark, after 3 years and 5 surgeries, success would mean beating the odds, and becoming of on Dr. Nowzaradan’s most impressive weight-loss patients ever, but failure would mean…

Pauline’s self-destructive behavior continues to be a problem; Chad strives to be a better father and husband as he continues his journey; June’s progress stalls when frequent travel and wedding…

As Steven heals from his weight loss surgery, his brother Justin finally decides to come to Texas to get the same procedure, but his feelings toward Steven immediately begin to…

A year since her weight loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat…

Lee’s anger issues continue to jeopardize his relationship with Rena and threatens to derail both of their weight loss journeys; a major life event sends Sarah into a depression that…

In the fourth year of his weight-loss journey, Sean struggles to get past the loss of his mother and live on his own; Dr. Now intervenes to control Sean’s eating…

Weighing over 600 lbs. each, Vianey and Allen are locked in a codependent relationship based on a shared love of food. As they head to Houston, they will soon find…

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father…

At over 700 pounds, Brianne undertakes a weight-loss journey to save her own life; she faces an unexpected challenge to her fragile progress when her husband suffers a heart attack…

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can’t go;…

Back on Dr. Nowzaradan’s program, James is suspected of cheating as he continues to gain weight and suffers a series of life-threatening illnesses; Cynthia continues to lose weight but seems…

Losing over 200 pounds, Doug is now an active part of his family’s lives and inspires a healthier lifestyle for them all. However, Doug’s eating disorder and trouble finding his…

Ashley hits an emotional wall and is desperate for skin surgery, but she is not losing any weight. After being evicted, Nicole is forced to move back to Ohio, which…

Brittani has lost over 400 lbs. in two years. As part of her next chapter, will she and Bill start to plan to expand their family? Lupe has struggled since…

A 24-year-old woman weighs more than 600 pounds and is fighting for her life after a difficult childhood with an abusive stepfather and drug-addicted mother.

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again.

Surgery enabled Laura’s independence but the complications nearly killed her and she’s terrified about the next skin surgery. Chay revealed to her family she was transgender but living life as…

After losing 250 lbs, Nikki is on her way to skin surgery that will transform her body. But when a close friend dies from weight loss surgery, Nikki’s progress goes…

Charity manages to lose over 400 pounds, but her daughter Charly becomes dangerously obese. Devastated by the death of her husband, Elroy, Milla must find a way to finally qualify…

A man who weighed 800 pounds is engaged, but must continue to lose weight; a woman is on the verge of independence if she qualifies for skin surgery.

Tanisha weighs around 600-lbs and she’s desperate to survive for her kids and avoid her mother’s tragic fate of dying at age 50 from super obesity. Now at 32, her…

Most of the extreme weight on Tracey’s body resides in her shockingly misshapen legs. They’re so massive with severe lymphedema, that gastric surgery is her only chance of survival. Will…

Diana, a once thin & active woman, is now a prisoner to her 620lb body. Desperate to break free of her food addiction, she trades the comfort of her home…

Michael’s massive 632lb body has left him completely dependent upon his family. If he doesn’t learn to control his anger issues around food, lose weight, and address the root of…

At 670 pounds Ashley must live in her parents’ home with her husband. Desperate to save her life and her marriage, she decides it’s time for a drastic change. Can…