Christina is a 22-year old married woman from South Haven, Mississippi, who hasn’t left her house in two years due to her size. Her doting family has enabled her and…

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley…

Liz has gone from being bedbound with lymphedemas on both legs, to standing and walking, but old fears are about to threaten her progress; if Jenn and Marissa can’t get…

For Milla Clark, after 3 years and 5 surgeries, success would mean beating the odds, and becoming of on Dr. Nowzaradan’s most impressive weight-loss patients ever, but failure would mean…

A year since her weight loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat…

Ashley hits an emotional wall and is desperate for skin surgery, but she is not losing any weight. After being evicted, Nicole is forced to move back to Ohio, which…

Surgery enabled Laura’s independence but the complications nearly killed her and she’s terrified about the next skin surgery. Chay revealed to her family she was transgender but living life as…

After losing 250 lbs, Nikki is on her way to skin surgery that will transform her body. But when a close friend dies from weight loss surgery, Nikki’s progress goes…

Charity manages to lose over 400 pounds, but her daughter Charly becomes dangerously obese. Devastated by the death of her husband, Elroy, Milla must find a way to finally qualify…

A man who weighed 800 pounds is engaged, but must continue to lose weight; a woman is on the verge of independence if she qualifies for skin surgery.

Tanisha weighs around 600-lbs and she’s desperate to survive for her kids and avoid her mother’s tragic fate of dying at age 50 from super obesity. Now at 32, her…

Most of the extreme weight on Tracey’s body resides in her shockingly misshapen legs. They’re so massive with severe lymphedema, that gastric surgery is her only chance of survival. Will…

Diana, a once thin & active woman, is now a prisoner to her 620lb body. Desperate to break free of her food addiction, she trades the comfort of her home…

Michael’s massive 632lb body has left him completely dependent upon his family. If he doesn’t learn to control his anger issues around food, lose weight, and address the root of…

At 670 pounds Ashley must live in her parents’ home with her husband. Desperate to save her life and her marriage, she decides it’s time for a drastic change. Can…

Dottie loves being a mom but, at over 600lbs, she’s on the verge of leaving her 2 young children motherless. She agrees to a drastic new diet, but her child’s…

At 42 years old, Angel is staring death in the face. She is struggling to make a positive change and be an active part of her partner and son’s lives….

650-lb Melissa struggles to get to her ideal weight.