James comes from a long line of family obesity and at 706lbs, is determined not to die in the same hospital bed that his father and sister did. James vows…

Seana is 23 and nearly 700 lbs, living at her mom’s house, depressed and anxious, her weight-gain threatening to take her last breath. Dr. Now can give her the tools…

Joyce needs home health care 24/7 and hasn’t left the house in years. But getting to Dr. Now in Houston is just the first step, and when he prescribes therapy…

Liz has gone from being bedbound with lymphedemas on both legs, to standing and walking, but old fears are about to threaten her progress; if Jenn and Marissa can’t get…

For Milla Clark, after 3 years and 5 surgeries, success would mean beating the odds, and becoming of on Dr. Nowzaradan’s most impressive weight-loss patients ever, but failure would mean…

Pauline’s self-destructive behavior continues to be a problem; Chad strives to be a better father and husband as he continues his journey; June’s progress stalls when frequent travel and wedding…

As Steven heals from his weight loss surgery, his brother Justin finally decides to come to Texas to get the same procedure, but his feelings toward Steven immediately begin to…

A year since her weight loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat…

Lee’s anger issues continue to jeopardize his relationship with Rena and threatens to derail both of their weight loss journeys; a major life event sends Sarah into a depression that…

In the fourth year of his weight-loss journey, Sean struggles to get past the loss of his mother and live on his own; Dr. Now intervenes to control Sean’s eating…

Weighing over 600 lbs. each, Vianey and Allen are locked in a codependent relationship based on a shared love of food. As they head to Houston, they will soon find…

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father…

At over 700 pounds, Brianne undertakes a weight-loss journey to save her own life; she faces an unexpected challenge to her fragile progress when her husband suffers a heart attack…

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can’t go;…

Diana, a once thin & active woman, is now a prisoner to her 620lb body. Desperate to break free of her food addiction, she trades the comfort of her home…

At 670 pounds Ashley must live in her parents’ home with her husband. Desperate to save her life and her marriage, she decides it’s time for a drastic change. Can…

26-year-old Sean weighs over 700-lbs with a massive growth protruding from his side and skin so stretched it is tearing apart. His mother is forced to change both of their…

Weighing over 700 pounds at 26-years-old, the clock is ticking on Ashley’s life. Ashamed of her body, she mostly hides at home. After bypass surgery, Ashley confronts medical setbacks and…

Weighing in at over 600-lbs, 37 year old Susan is committed to drastic weight loss. But, when an unforeseen medical disorder strikes her mobility, finding the strength to make it…

At just 24, Bettie Jo is eating her way towards 700-lbs. Housebound, she is reliant on her husband for even basic needs. Bettie Jo’s future relies on her losing weight,…

Chuck weighs almost 700lbs and it has hindered every aspect of his life. He’s had to downsize his business and his wife feels like a single-parent, who is ready to…