At nearly 700 lbs., 51-year-old Pauline has an addiction to food that is killing her and taken over the life of her son, who is the primary caretaker. Can she…

For Larry, a second weight loss surgery would mean a second chance at a career as a gospel recording artist. But a beautiful singing voice doesn’t pair well with a…

Margaret’s life at 700 pounds is in need of a jump start. At age 35, she is a mama’s girl. Now, it’s time for Margaret to get out of bed,…

Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now’s help with a second weight-loss surgery. But just when the…

Having her daughters help bathe her is not how Chrystal pictured parenting, but she is so large now that there’s no other option. Chrystal wants Dr. Now’s help, but she…

Dominic’s life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only…

Seana is 23 and nearly 700 lbs, living at her mom’s house, depressed and anxious, her weight-gain threatening to take her last breath. Dr. Now can give her the tools…

For Milla Clark, after 3 years and 5 surgeries, success would mean beating the odds, and becoming of on Dr. Nowzaradan’s most impressive weight-loss patients ever, but failure would mean…

Lee’s anger issues continue to jeopardize his relationship with Rena and threatens to derail both of their weight loss journeys; a major life event sends Sarah into a depression that…

Kelly is on the verge of immobility when she decided to make the trip to Houston to visit Dr. Now; Her journey gets off to a painful start when a…

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can’t go;…

Back on Dr. Nowzaradan’s program, James is suspected of cheating as he continues to gain weight and suffers a series of life-threatening illnesses; Cynthia continues to lose weight but seems…

Melissa has lost 500 pounds and saw her weight drop to 137 pounds, but now faces marital problems and life as a single mom, all while struggling with a gain…

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight…

A devoted girlfriend and loving aunt, Alicia is all smiles and laughter on the outside, but on the inside she is terrified that her addiction to food will kill her…

Dr. Nowzaradan is worried Lupe’s emotional issues are blocking her weight loss journey since she’s shed over 300 lbs. but still can’t walk. Ashley is struck with sudden paralysis. Sarah…

Tanisha weighs around 600-lbs and she’s desperate to survive for her kids and avoid her mother’s tragic fate of dying at age 50 from super obesity. Now at 32, her…

Steven Assanti weighs nearly 800-lbs and his brother/nemesis, Justin, is almost 600-lbs. Though the brothers can’t stand each other, their father packs up the family to travel across the country…

After overcoming a dependence on drugs & alcohol, sneaking food is 660-lb Doug’s last remaining vice. Can this husband, and father of 3 overcome his addictive personality and take control…

Michael’s massive 632lb body has left him completely dependent upon his family. If he doesn’t learn to control his anger issues around food, lose weight, and address the root of…

Cynthia is a 610-lb single mother raising five kids. She’s been focused on her children, but now realizes what her death would mean for them. As she battles her emotions…

At 700 pounds, Chad’s weight is dangerously out of control. After gastric bypass surgery, he quickly sheds pounds but faces a medical crisis when he does not follow the doctor’s…

Laura has used food to cope with her emotions for too long. Confined to a wheelchair, relying on an oxygen tank to breathe, she depends upon her husband and mother…

Charity weighs nearly 800-lbs. Suffering from flesh-eating bacteria and butterfly shaped fat deposits; she is unable to function without help form her family. When unexpected bad news threatens her weight…

Chay is just 23, but to cope with the emotional turmoil of his childhood he has eaten his way to 600-lbs and it’s threatening to kill him before turning 30….

Marla is so heavy she cannot stand up. Bedridden, her true weight is unknown but estimated at 800-lbs. Marla must face the facts about her health and the toll it…

Weighing in at over 600-lbs, 37 year old Susan is committed to drastic weight loss. But, when an unforeseen medical disorder strikes her mobility, finding the strength to make it…

At just 24, Bettie Jo is eating her way towards 700-lbs. Housebound, she is reliant on her husband for even basic needs. Bettie Jo’s future relies on her losing weight,…

At 42 years old, Angel is staring death in the face. She is struggling to make a positive change and be an active part of her partner and son’s lives….

Joe is only 30, and trapped in an 800-lb body. He lost his job and is mostly housebound. Can Joe find the strength to face his past and save his…

At age 23, and over 600-lbs, Amber relies on her family, and boyfriend for even simple needs. Her fear of dying young is so overwhelming that she makes the decision…

Bedridden for four years, 46-year old Penny knows that her weight may kill her if drastic actions aren’t taken. Penny moves from Maryland to Texas, to have gastric bypass –…

Love motivates 660-lb Donald to begin his weight loss journey.