At 700lbs, Milla is bedridden and dependent on her husband and five kids. Terrified each day will be her last, they still can’t resist her unending requests for junk food….

26-year-old Sean weighs over 700-lbs with a massive growth protruding from his side and skin so stretched it is tearing apart. His mother is forced to change both of their…

At 600 pounds, Lupe spent the last 10 years in bed & totally dependent on her husband. A doctor in Texas is her only hope for change. A cross-country move…

Lifelong secret eater Nikki finds her life and career as a costume designer threatened by immobility as her weight climbs to 650-lbs. In urgent need of drastic weight loss, she…

Lisa wouldn’t have made it this far without the help of her chief enabler, her boyfriend Randy. But Randy falls ill, and Lisa is about to find out if she…

Living on a homestead with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can’t take off. All he does is eat and game,…

Mike was born with a talent for sports — and an omnivorous appetite to match. After his football dreams were dashed by multiple concussions, he packed on over 700 pounds….

Shannon’s husband loves her the way she is, but that may not help because she’s 700 pounds and bedridden. Dr. Now knows it’s not easy to break a toxic cycle…

At 24 years old and over 600 lbs, Megan lives at home with her mom, who cooks for her since Megan can’t do much on her own; Megan must travel…

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley…

J.T. is almost 900lbs with a 100-lb lymphedema mass on his leg and a food addiction that is bound to kill him if he doesn’t change. His girlfriend takes him…

When Annjeanette was nine, a campaign was established to send her to fat camp; she hated that her weight had become a source of public shame and she has struggled…

A 400-lb. woman learns that she’s pregnant, but wonders if she’ll be able to deliver the baby without complications; a woman who lost 400 pounds is in a relationship, but…

A 24-year-old woman weighs more than 600 pounds and is fighting for her life after a difficult childhood with an abusive stepfather and drug-addicted mother.

Jennifer and her daughter, Marissa, are stuck in a co-dependent relationship that puts both of their lives in jeopardy, with a combined weight of more than 900 pounds; Jennifer strives…

After a year on a weight loss program, Steven remains completely non-compliant, and Justin focuses on a new career instead of his diet. With neither brother close to being approved…

750-lb Henry begins his weight loss journey in the hopes of transforming himself in time to attend his high school reunion.