At 650 pounds, Gideon’s weight prohibits him from working, making him completely dependent on his exhausted wife. Desperate for change, he uproots his family to restart his life with weight-loss…

Lisa wouldn’t have made it this far without the help of her chief enabler, her boyfriend Randy. But Randy falls ill, and Lisa is about to find out if she…

Living on a homestead with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can’t take off. All he does is eat and game,…

Mike was born with a talent for sports — and an omnivorous appetite to match. After his football dreams were dashed by multiple concussions, he packed on over 700 pounds….

Shannon’s husband loves her the way she is, but that may not help because she’s 700 pounds and bedridden. Dr. Now knows it’s not easy to break a toxic cycle…

At 24 years old and over 600 lbs, Megan lives at home with her mom, who cooks for her since Megan can’t do much on her own; Megan must travel…

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley…

J.T. is almost 900lbs with a 100-lb lymphedema mass on his leg and a food addiction that is bound to kill him if he doesn’t change. His girlfriend takes him…

Joyce needs home health care 24/7 and hasn’t left the house in years. But getting to Dr. Now in Houston is just the first step, and when he prescribes therapy…

In the fourth year of his weight-loss journey, Sean struggles to get past the loss of his mother and live on his own; Dr. Now intervenes to control Sean’s eating…

When Annjeanette was nine, a campaign was established to send her to fat camp; she hated that her weight had become a source of public shame and she has struggled…

A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food; only the help of Dr….

Losing over 200 pounds, Doug is now an active part of his family’s lives and inspires a healthier lifestyle for them all. However, Doug’s eating disorder and trouble finding his…

Brittani has lost over 400 lbs. in two years. As part of her next chapter, will she and Bill start to plan to expand their family? Lupe has struggled since…

A 400-lb. woman learns that she’s pregnant, but wonders if she’ll be able to deliver the baby without complications; a woman who lost 400 pounds is in a relationship, but…

A 24-year-old woman weighs more than 600 pounds and is fighting for her life after a difficult childhood with an abusive stepfather and drug-addicted mother.

Jennifer and her daughter, Marissa, are stuck in a co-dependent relationship that puts both of their lives in jeopardy, with a combined weight of more than 900 pounds; Jennifer strives…

Charity manages to lose over 400 pounds, but her daughter Charly becomes dangerously obese. Devastated by the death of her husband, Elroy, Milla must find a way to finally qualify…

After a year on a weight loss program, Steven remains completely non-compliant, and Justin focuses on a new career instead of his diet. With neither brother close to being approved…

Weighing over 600-lbs Kirsten is close to losing her mobility. While she’s trying to get control of her obesity she’s also in danger of losing her troubled son. She must…

At 700lbs, Milla is bedridden and dependent on her husband and five kids. Terrified each day will be her last, they still can’t resist her unending requests for junk food….

26-year-old Sean weighs over 700-lbs with a massive growth protruding from his side and skin so stretched it is tearing apart. His mother is forced to change both of their…

At 600 pounds, Lupe spent the last 10 years in bed & totally dependent on her husband. A doctor in Texas is her only hope for change. A cross-country move…

Weighing over 700 pounds at 26-years-old, the clock is ticking on Ashley’s life. Ashamed of her body, she mostly hides at home. After bypass surgery, Ashley confronts medical setbacks and…

At over 700lbs, Teretha’s life is confined to a bed which is a far cry from her former job representing Detroit’s healthy eating program. Her adoring family fears losing her…

At 650lbs, Randy’s food addiction led to the loss of his marriage and visits with his daughter. To regain control of his life, he endures a rigorous pre-surgery diet, surrounded…

Brittani married a man who loves large women but at 600 lbs she can barely contribute to their marriage. With dreams of a normal relationship, she gets weight loss surgery….

At 700 pounds, Chad’s weight is dangerously out of control. After gastric bypass surgery, he quickly sheds pounds but faces a medical crisis when he does not follow the doctor’s…

600-pound June copes with the tragic death of her son by eating. After gastric bypass surgery, she must confront the emotional issues driving her food compulsion. If she can stay…

Dottie loves being a mom but, at over 600lbs, she’s on the verge of leaving her 2 young children motherless. She agrees to a drastic new diet, but her child’s…

Lifelong secret eater Nikki finds her life and career as a costume designer threatened by immobility as her weight climbs to 650-lbs. In urgent need of drastic weight loss, she…

At just 24, Bettie Jo is eating her way towards 700-lbs. Housebound, she is reliant on her husband for even basic needs. Bettie Jo’s future relies on her losing weight,…

At 42 years old, Angel is staring death in the face. She is struggling to make a positive change and be an active part of her partner and son’s lives….

Bedridden for four years, 46-year old Penny knows that her weight may kill her if drastic actions aren’t taken. Penny moves from Maryland to Texas, to have gastric bypass –…

Chuck weighs almost 700lbs and it has hindered every aspect of his life. He’s had to downsize his business and his wife feels like a single-parent, who is ready to…

Battling severe depression in the wake of a suicide attempt, 46-year old Olivia hasn’t left her Chicago basement in two years. With one last chance at a new life, Olivia…

750-lb Henry begins his weight loss journey in the hopes of transforming himself in time to attend his high school reunion.