Dr. Nowzaradan is worried Lupe’s emotional issues are blocking her weight loss journey since she’s shed over 300 lbs. but still can’t walk. Ashley is struck with sudden paralysis. Sarah…

Growing up in foster care, David suffered from a lack of attention and didn’t develop a sense of self-worth. Now he weighs 800 pounds, and he’s relying on his favorite…

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley…

When Annjeannette was 9, a campaign was established to send her to fat camp. She hated that her weight had become a source of public shame and she has struggled…

A 400-lb. woman learns that she’s pregnant, but wonders if she’ll be able to deliver the baby without complications; a woman who lost 400 pounds is in a relationship, but…

Melissa has lost 500 pounds and saw her weight drop to 137 pounds, but now faces marital problems and life as a single mom, all while struggling with a gain…