A 400-lb. woman learns that she’s pregnant, but wonders if she’ll be able to deliver the baby without complications; a woman who lost 400 pounds is in a relationship, but…

Melissa has lost 500 pounds and saw her weight drop to 137 pounds, but now faces marital problems and life as a single mom, all while struggling with a gain…

Fearing that he’ll suffer the same fate as older brother David, now 700 pounds and unable to work, Benji hopes to be able to support both himself and his brother…

A former plus-size model and “big is beautiful” advocate, Renee realizes the mortal mistakes she made as her weight swells to 600 pounds and her health crumbles.

A 24-year-old woman weighs more than 600 pounds and is fighting for her life after a difficult childhood with an abusive stepfather and drug-addicted mother.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight…

Jennifer and her daughter, Marissa, are stuck in a co-dependent relationship that puts both of their lives in jeopardy, with a combined weight of more than 900 pounds; Jennifer strives…

After meeting and falling in love at a bariatric rehab center, Lee and Rena are battling health and anger issues while making a desperate, second attempt to save their lives.

Growing up in foster care, David suffered from a lack of attention and didn’t develop a sense of self-worth. Now he weighs 800 pounds, and he’s relying on his favorite…

Lisa wouldn’t have made it this far without the help of her chief enabler, her boyfriend Randy. But Randy falls ill, and Lisa is about to find out if she…

For Larry, a second weight loss surgery would mean a second chance at a career as a gospel recording artist. But a beautiful singing voice doesn’t pair well with a…

Dolly has gotten too comfortable at 600 pounds. There’s physical pain all over, and the skin apron pulling on her abdomen is miserable, but with her mom and others waiting…

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he’s training to become a minister. But if he can’t find a way to…

Margaret’s life at 700 pounds is in need of a jump start. At age 35, she is a mama’s girl. Now, it’s time for Margaret to get out of bed,…

Living on a homestead with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can’t take off. All he does is eat and game,…

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won’t survive if he moves to…

Ryan moved to Montana to keep himself from going down a dark path of drug addiction. However, his new path may be no less lethal than the last if he…

For James B, food means family. He grew up eating rich Haitian food and loves it with a passion. Now, James needs Dr. Now’s help to diminish that love in…

For Julian and his wife, Irma, it was love at first sight. But in order to grow old together, Julian will have to overcome the food addiction that made him…

Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now’s help with a second weight-loss surgery. But just when the…

Mike was born with a talent for sports — and an omnivorous appetite to match. After his football dreams were dashed by multiple concussions, he packed on over 700 pounds….

Lacey is so big from overeating that she can barely leave the house, but that hasn’t stopped her from finding love with Ricky. Her weight isn’t the only thing between…

When Nathan’s weight gets in the way of the only healthy thing in his life – his job as a drama teacher – it’s a wake-up call for him. But…

Having her daughters help bathe her is not how Chrystal pictured parenting, but she is so large now that there’s no other option. Chrystal wants Dr. Now’s help, but she…

Through tough times, food has always been Tammy’s friend. But now she has gotten so big that her daughters and mother have moved home to care for her, and unless…

Shannon’s husband loves her the way she is, but that may not help because she’s 700 pounds and bedridden. Dr. Now knows it’s not easy to break a toxic cycle…

Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can’t get through to her, the only…

Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10. While learning to cook for his family, he began comfort-eating. Now to avoid eating…

The four best reasons for Coliesa to live are her daughters. But after a heart attack and losing the love of her life in a car crash, Coliesa eats non-stop…

Dominic’s life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only…

At 24 years old and over 600 lbs, Megan lives at home with her mom, who cooks for her since Megan can’t do much on her own; Megan must travel…

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley…

At 600 pounds, Ashley has to move home so her mom can help her care for herself and her newborn daughter; Ashley must overcome a lifetime’s worth of unfortunate circumstances…

Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of, but to break the cycle of pathological eating, he’ll have to…

J.T. is almost 900lbs with a 100-lb lymphedema mass on his leg and a food addiction that is bound to kill him if he doesn’t change. His girlfriend takes him…