Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith’s house, but their haggard appearance speaks volumes to everyone – including Bailey, who warns…

Meredith grows increasingly dissatisfied with the unknown details of Derek’s life. Meanwhile, Alex treats Devo, a patient whose religious beliefs jeopardize her chances for recovery; Izzie contemplates reconnecting with her…

A sexually transmitted disease breaks out and affects several members of the hospital staff. Chief Webber promptly calls a meeting. Meanwhile, the chief reluctantly tells Dr. Derek Shepherd about his…

While George is feeling a little less masculine because of the way Izzie and Meredith have been treating him (like a sister), Izzie is assigned to a patient about to…

Meredith realizes that she must take on a lot more responsibility when she is told that her mother needs to sign over all of her assets to her. As Izzie…

Izzie tries to get George to find the courage to ask Meredith out. All of the interns are in awe when a woman comes in with a record breaking tumor,…

Meet Meredith Grey. Daughter of famous surgeon Ellis Grey and currently recovering from a one-night stand. She shoos away her evening’s companion, saying she’ll be late for her first day…

The surgical staff tries to be optimistic as a young woman clings to life after a brutal attack. Meanwhile Meredith puts her career on the line to save a newborn…

A bike race injures several pedestrians as well as well as participants. One pedestrian is left brain dead. Christina and Issie wish to use his organs for organ donation but…

Sam and Dean investigate an abandoned sanitarium and discover that when the hospital was open, the patients held a revolt against the cruel and unusual punishments inflicted by the head…

After a construction worker is killed by insects burrowing into his brain, Sam and Dean investigate the town’s history and find that the new housing development is being built on…

Sam is haunted by a vision of a woman trapped in his childhood house and convinces a reluctant Dean that they need to go home. Upon arrival, they meet the…

In suburban Nebraska, a group of partying high school teens jokingly dare their friend Charlie to look into the mirror and repeat “Bloody Mary, Bloody Mary, Bloody Mary,” not knowing…

Sam and Dean come to the aid of Sam’s old college buddy after he is accused of a murder he swears he didn’t commit. The brothers discover a shapeshifter is…

The infamous “Hook Man,” a vengeful spirit who kills his victims with a shiny hook that serves as his hand, terrorizes a small college town in Iowa. Sam and Dean…

On TransNational flight 2485, a man possessed by the spirit of the Phantom Traveler causes the plane to crash, leaving only five survivors left alive. Sam and Dean must exorcise…

Sam and Dean follow the coordinates left in their father’s journal and land in the middle of the woods where they investigate the disappearance of several campers. The two brothers…

Sam and Dean investigate a series of mysterious drownings written off as suicides. They discover the spirit is an angry little boy with the power to travel through water who…

Two brothers, Sam and Dean Winchester, witness their mother’s paranormal death as children and grow up trained to fight by a distraught father who wants nothing more then to hunt…